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Nearly 7 million people in the San Francisco area were all but confined to their homes Tuesday in the nation's most sweeping lockdown against the coronavirus, even as spring break crowds partied in Florida and tourists lined up to pose for pictures in front of the world-famous “Welcome to Las Vegas” sign.

Arizona, Florida and Illinois pressed ahead with their presidential primaries, recommending such precautions as putting tape on the floor to keep voters a safe distance apart, while Ohio called off its election hours before the polls were to open.

The official reaction to the crisis varied wildly across the U.S., despite new, more urgent warnings from the Trump administration, which called on Americans not to gather in groups of more than 10 and advised older people to stay home.

Coronavirus infections across the country reached approximately 4,700, and the death toll climbed to at least 93, with more than half of the victims from Washington state. Worldwide, more than 7,300 have died.

Dr. Deborah Birx, coordinator for the federal response to the virus, called on the "army of millennials" to lead the charge. Birx said on ABC's "Good Morning America" that the nation needs young adults doing everything they can to avoid infection, but also protecting their parents and grandparents.

Birx has said that millennials, those born in the 1980s and early ’90s, are vital to stopping the spread of the virus, in part because they grew up with social media and understand how to work and communicate without meeting in person.

But not all those millennials were listening. With beaches on Florida’s Gulf coast near Tampa still open, at least one was full of spring breakers. Gov. Ron Desantis said he would leave beach restrictions up to local authorities.

"It's not probably advisable to have spring break gatherings," but small beach groups are probably OK, he said. “I think the communities can work that out."

Texas Gov. Greg Abbott, a Republican, praised the federal government's response as he took only limited action amid the outbreak. Unlike other governors of heavily populated states, Abbott has not made explicit calls for limiting mass gatherings.

“This is not a time to panic," he said. “It’s not as if we have never been through this before. We’ve been through this many, many times."

As the U.S. economy ground to a near-halt, stocks bounced around in early trading Tuesday on Wall Street, one day after the worst market loss since the Black Monday crash of 1987.

The rapid work stoppage had Americans fretting about their jobs and their savings, threatened to overwhelm unemployment benefit programs, and heightened fears the country could plunge into a recession.

The president acknowledged for the first time that the outbreak may send the economy into a recession and suggested that the nation may be dealing with the virus until July or August.

Election officials in the three states holding primaries said they were taking precautions to make sure voters could safely cast their ballots. The immediate problem: Hundreds of poll workers dropped out, forcing state officials to scramble.

"Please, please heed our call and volunteer," said Marisel Hernandez, head of the election commission in Chicago. "Help us."

Election officials in Illinois' Cook County, home to Chicago, urged poll workers to use blue painter’s tape to mark the floor every 6 feet so voters could keep their distance while waiting in line.

Meanwhile, millions of Americans were holed up at home, with many thrown out of work until further notice as the list of businesses forced to close across the U.S. extended to restaurants, bars, gyms and casinos.

In Detroit, bus riders were stranded Tuesday after most drivers didn't report to work, apparently concerned about the spread of the virus and confused as to whether Michigan's new restrictions on gatherings included vehicles loaded with commuters.

The city canceled bus service shortly after 8 a.m. because of the shortage of drivers. Surprised riders waiting at stops across the city pulled out phones to try to get a lift from friends or family.

“Just now?" a maintenance man, Amadou Sanders, asked. “How am I going to get to work?”

Officials in six San Francisco Bay Area counties issued a “shelter-in-place” order affecting millions, requiring most residents to stay inside and venture out only for food, medicine or exercise for three weeks.

"I know today’s order is a radical step. It has to be. We need to act now, all of us," said Dr. Grant Colfax, director of the San Francisco Health Department.

Health officials say that "social distancing" — encouraging people to avoid close contact with others — is a key to slow the spread of the virus and keep U.S. hospitals from being overwhelmed with a sudden deluge of patients.

Most people who come down with the disease have relatively mild symptoms, but it can be deadly for some, especially the elderly and those with underlying health problems. Most people infected with the virus recover in a matter of weeks.

The shutdowns touched every corner of the country: blackjack dealers in Las Vegas, theme park workers in Orlando, Florida, restaurant and bar employees nationwide, and winery workers in California. At least eight states called on all bars and restaurants to close at least part of the day.

With schools closed for tens of millions of children across the country, parents helped their youngsters with take-home lesson plans. Many did this while juggling work conference calls, emails and memos. Others scrambled to find child care.

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Associated Press writers Ed White in Detroit, Angela Charlton in Paris; Geir Moulson in Berlin; Kelli Kennedy and Terry Spencer in Fort Lauderdale, Florida; Mike Schneider in Orlando, Florida; Sophia Tareen and Tammy Webber in Chicago; John O'Connor in Springfield, Illinois; Christina A. Cassidy in Atlanta; Julie Watson in San Diego and Olga R. Rodriguez in San Francisco contributed to this report.

Copyright 2020 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed without permission.

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